Know How
"The tragedy of life doesn’t lie in not reaching your goal. The tragedy lies in having no goals to reach"
Benjamin Mays
Active consulting
Scientific consultant
Study and development of proteins downstream processes from plants (rice and tobacco). Scale-up of protein extraction, clarification, capture and polishing processes. Production of preclinical batches. Production facilities. Implants validation.
Project leader
Scientific Consultant. Partnership with a major Italian university and an hospital company, for study and development of innovative biotechnological products in various areas such as obesity, celiac disease, vaccines, trichology, psoriasis and oral hygiene.
JOB EXPERIENCES
Founding partner
Advising companies engaged in biotechnological research related to development of innovative products in pharmaceutical, chemicals, medical devices, food supplements and cosmetics sectors
Head of the Biochemistry Department
Study and production of proteins and enzymes from biomass. Study of cells metabolism, monitoring by-products during fermentation and applying the results to achieve higher productivity. Management of the department's material and equipment requirements with extensive autonomy. Management of technical staff and/or graduates assigned to the department. Participation in drafting and reporting on funded research projects.
Analytical development methods
Development of analytical methods for pharmaceutical products control, with particular focus on antibiotics. Degradation tests, and stability studies. Gas-chromatography methods. Validation of methods.
Researcher
Study and development of proteins purification processes and chemical molecules by mammalian cells and bacteria, from laboratory to industrial scale. Validation of production implants (chromatographs, management systems, ultrafiltration systems etc.) with drafting of operating procedures. Management and training of technical auxiliary personnel.
Researcher
Biochemistry researcher with task of study and development of downstream process to produce peptides from snake venom fractions. Development of HPLC methods for chemical molecules characterisation. Management of stability studies
Quality Control
Control of finished and semi-finished products, raw materials and packaging. Management of stability studies. Management and training of auxiliary staff. Study and development of new analytical methods. Drafting operational procedures.
Scientific publications
Patents
Courses and workshops
Two different validation studies of purification processes inherent to viral inactivation/removal . Expanded bed adsorption. Tangential flow filtration and preparative low-pressure chromatography. HPLC Analytical method and validation Monoclonal Antibodies expression and production. Scale up And Technical transfer Various courses on GLP standards and HPLC analytical methods validation. Various theoretical/practical courses about ultrafiltration systems scale up. Several theoretical and practical courses about use of analytical chromatographic systems and management software.